Biochemical characterization of a new melanoma model-the minipig MeLim strain

0213634 - UZFG-Y 20033103 RIV GB eng J - Článek v odborném periodiku
Borovanský, J. - Horák, Vratislav - Elleder, M. - Fortýn, Karel - Smit, P. M. - Kolb, A. M.
Biochemical characterization of a new melanoma model-the minipig MeLim strain.
Melanoma Research. Roč. 13, - (2003), s. 543-548. ISSN 0960-8931. E-ISSN 1473-5636
Grant CEP: GA AV ČR KSK5011112; GA ČR GA524/01/0162
Výzkumný záměr: CEZ:AV0Z5045916
Klíčová slova: melanoma * tyrosinase * devitalization
Kód oboru RIV: FD - Onkologie a hematologie
Impakt faktor: 2.190, rok: 2003

Hereditary mminipig melanomas which have many histopathological and other features in common with their human counterparts, have recently become preffered melanoma models.The MeLiM strain was selected by partial inbreeding. A high tumour incidence and malignant behaviour on the one hand together with the occurrence of spontaneous regression and high susceptibillity to the devitalization technique as a new strategy in melanoma therapy, make the MeLiM strain a superior melanoma model to other hereditary swine melanomas.
Trvalý link: http://hdl.handle.net/11104/0109169