Počet záznamů: 1
Synthesis of .I.N./I..sup.4./sup.-alkyl-5-azacytidines and their base-pairing with carbamoylguanidines - a contribution to explanation of the mutagenicity of 2'-deoxy-5-azacytidine
- 1.0194799 - UOCHB-X 20030105 RIV CZ eng J - Journal Article
Pískala, Alois - Hanna, N. B. - Masojídková, Milena - Otmar, Miroslav - Fiedler, Pavel - Ubik, Karel
Synthesis of .I.N./I.4-alkyl-5-azacytidines and their base-pairing with carbamoylguanidines - a contribution to explanation of the mutagenicity of 2'-deoxy-5-azacytidine.
Collection of Czechoslovak Chemical Communications. Roč. 68, č. 4 (2003), s. 711-743. ISSN 0010-0765
Institutional research plan: CEZ:AV0Z4055905
Keywords : nucleosides * cytostatic activity * nucleobase pairs
Subject RIV: CC - Organic Chemistry
Impact factor: 1.041, year: 2003
A series of .I.N./I.4-alkyl-5-azacytidines was prepared and a formation of aggregates with their hydrolytical products were observed. On the basis of hydrogen bonding in these aggregates the mechanism of the mutagenicity of 2'-deoxy-5-azacytosine was hypothesized.
Permanent Link: http://hdl.handle.net/11104/0090470
Počet záznamů: 1