Počet záznamů: 1
Desoctapeptideinsulin fragments formed by chymotryptic cleavage and suitable for modification of insulin in positions A 14 and B 16
- 1.0193689 - UOCHB-X 20000039 RIV SIGLE CZ eng C - Konferenční příspěvek (zahraniční konf.)
Koubová, V. - Barthová, J. - Kašička, Václav - Ubik, Karel - Barth, Tomislav - Bezouška, K.
Desoctapeptideinsulin fragments formed by chymotryptic cleavage and suitable for modification of insulin in positions A 14 and B 16.
80-86241-06-8. In: Biologically Active Peptides. Praha: ÚOCHB AVČR, 1999 - (Slaninová, J.; Barth, T.), s. 88-90. Collection Symposium Series., 3.
[Biologically Active Peptides. Conference /6./. Praha (CZ), 21.04.1999-23.04.1999]
Grant CEP: GA MPO PZ-Z2/32
Výzkumný záměr: CEZ:AV0Z4055905
Klíčová slova: DOI-Fragments
Kód oboru RIV: CE - Biochemie
The molecule of desoctapeptide insulin is cleaved by ŕ-chymotrypsin at the three tyrosine residues. The fragments with tyrosine C-terminal residues are candidates of semisynthetic modification. They were isolated and characterized by HPLC, capillary electrophoresis and mass spectrometry.
Trvalý link: http://hdl.handle.net/11104/0089384
Počet záznamů: 1