Počet záznamů: 1
Utilization of oncoprotein-pulsed dendritic cells as tumor vaccines
- 1.0191236 - UMG-J 20010307 RIV DE eng J - Článek v odborném periodiku
Bubeník, Jan
Utilization of oncoprotein-pulsed dendritic cells as tumor vaccines.
Journal of Cancer Research and Clinical Oncology. Roč. 127, č. 8 (2001), s. 463-466. ISSN 0171-5216. E-ISSN 1432-1335
Grant CEP: GA MZd NC5526; GA MZd NC45011; GA ČR GA312/98/0826; GA ČR GA312/99/0542; GA ČR GA301/00/0114
Výzkumný záměr: CEZ:AV0Z5052915
Klíčová slova: dendritic cells * tumor vaccines * oncoproteins
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 2.194, rok: 2001
Dendritic cells are the most potent professional antigen-presenting cells. This capability makes them attractive vehicles for the delivery of therapeutic cancer vaccines. The lack of tumor antigen presentation on mature DCs in vivo can be bypassed by direct loading of DCs with oncoproteins in vitro. Several aspects of utilization of oncoprotein-pulsed DCs as tumor vaccines are discussed.
Trvalý link: http://hdl.handle.net/11104/0086992
Počet záznamů: 1