Počet záznamů: 1
Expression profiles and intergenic structure of head-to-head oriented Brca1 and Nbr1 genes
- 1.0191202 - UMG-J 20010273 RIV NL eng J - Článek v odborném periodiku
Dimitrov, Stoil - Brennerová, Mária - Forejt, Jiří
Expression profiles and intergenic structure of head-to-head oriented Brca1 and Nbr1 genes.
Gene. Roč. 262, 1-2 (2001), s. 89-98. ISSN 0378-1119. E-ISSN 1879-0038
Grant CEP: GA ČR GA301/99/0354; GA ČR GV204/98/K015; GA AV ČR IAA5052709
Grant ostatní: HHMI(US) 75195540303
Výzkumný záměr: CEZ:AV0Z5052915
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 3.041, rok: 2001
Mouse and human .I.Brca1-BRCA1 ./I.and .I.Nbr1-NBR2 ./I.genes liehead-to-head, being transcribed from the opposite strands. Weanalyzed expression profiles of .I.Brca1 ./I.and a newly identifiedisoform of .I.Nbr1 ./I.in spermatogenesis. In adult mouse testis,the expression of the new .I.Nbr1 (1a) ./I.isoform was confined mainly to spermatids. The expression profile of .I.Brca1 ./I. paralleled that of .I.Nb./I.r.I.1 (1b)./I.. The newly defined intergenic region (289 bp) between .I.Nbr1 ./I.and .I.Brca1 ./I.in the mouse and rat corresponds well to the human .I.BRCA1-NBR2 ./I.region.
Trvalý link: http://hdl.handle.net/11104/0086959
Počet záznamů: 1