A nonspecific, single-stranded nuclease activity with characteristics of a topoisomerase found in a major grass pollen allergen: Possible biological significance

0189896 - UMBR-M 20023002 RIV DE eng J - Článek v odborném periodiku
Bufe, A. - Uhlig, U. - Scholzen, T. - Matoušek, Jaroslav - Schlaak, M. - Weber, W.
A nonspecific, single-stranded nuclease activity with characteristics of a topoisomerase found in a major grass pollen allergen: Possible biological significance.
Biological Chemistry. Roč. 380, - (1999), s. 1009-1016. ISSN 1431-6730. E-ISSN 1437-4315
Klíčová slova: grass allergens * pollen * biological activity
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 3.356, rok: 1999

The major allergen from timothy grass pollen, Phlp5b (Phleum pratense), was shown to exhibit ribonuclease activity. It turned out that the C-terminal portion of this molecule was the biologically active domain. Here evidence is presented that the allergen is a single-stranded, sugar-nonspecific nuclease with topoisomerase activity.
Trvalý link: http://hdl.handle.net/11104/0085693