0188340 - UMCH-V 20010113 RIV US eng C - Conference Paper (international conference)
Rypáček, František - Machová, Luďka - Kotva, Rudolf - Škarda, Václav
Polyesters with functional-peptide blocks: Synthesis and application to biomaterials.
Polymeric Materials: Science and Engineering. San Diego: Americal Chemical Society, 2001, s. 817-818. ISBN 0-8412-3787-5.
[Spring Meeting. San Diego (US), 01.04.2001-05.04.2001]
R&D Projects: GA ČR GA203/99/0576; GA AV ČR KSK4055109
Institutional research plan: CEZ:AV0Z4050913
Keywords : block copolymers * synthesis * polylactide
Subject RIV: CD - Macromolecular Chemistry

Novel approach to the synthesis of block copolymers contaiing polylactide and poly(amino acid) blocks is presented. Controlled living polymerization of amino acid N-carboxyanhydrides is used to build cell-adhesive RGD peptide sequences at the end of the poly(amino acid) block. Functional block copolymers can be used to control interactions of cells with surfaces of biodegradable polymer materials.
Permanent Link: http://hdl.handle.net/11104/0084303