A Link between the p53 germ line polymorphisms and white blood cells apoptosis in lung cancer patients

0173579 - UEM-P 20023024 RIV NL eng J - Článek v odborném periodiku
Biroš, Erik - Kohút, A. - Biroš, I. - Kalina, I. - Bogyiová, E. - Štubňa, J.
A Link between the p53 germ line polymorphisms and white blood cells apoptosis in lung cancer patients.
Lung Cancer. Roč. 35, č. 3 (2002), s. 231-235. ISSN 0169-5002. E-ISSN 1872-8332
Grant CEP: GA MŽP SI/340/1/97
Výzkumný záměr: CEZ:AV0Z5039906
Klíčová slova: apoptosis * p53 polymorphism * lung cancer
Kód oboru RIV: FD - Onkologie a hematologie
Impakt faktor: 2.451, rok: 2002

A possible relationship between the p53 polymorphisms and apoptosis was investigated. The study focused on two polymorphisms (p53 BstUI SNP on the 4th exon and p53 MspI SNP on the 6th exon) in relation to apoptosis of white blood cells in lung cancer patients and healthy controls were studied. Obtained results suggest that p53 BstUI and p53 MspISNP may play a certain role in p53 dependent apoptotic pathway.
Trvalý link: http://hdl.handle.net/11104/0070610