The evolutionary history of kinetoplastids and their kinetoplasts

0157585 - PAU-O 20023060 RIV US eng J - Článek v odborném periodiku
Simpson, A. G. B. - Lukeš, Julius - Roger, A. J.
The evolutionary history of kinetoplastids and their kinetoplasts.
Molecular Biology and Evolution. Roč. 19, č. 12 (2002), s. 2071-2083. ISSN 0737-4038. E-ISSN 1537-1719
Grant CEP: GA ČR GA204/00/1212
Výzkumný záměr: CEZ:AV0Z6022909
Klíčová slova: Kinetoplastida * kinetoplast * evolution
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 5.271, rok: 2002

Despite extensive phylogenetic analysis of small subunit ribosomal RNA (SSUrRNA) genes, the deep-level relationships among kinetoplastids remain poorly understood, limiting our grasp of their evolutionary history, especially the origins of their bizarre mitochondrial genome organizations. In this study we examine the SSUrRNA data in the light of a new markerÚcytoplasmic heat shock protein 90 (hsp90) sequences. Our phylogenetic analyses divide kinetoplastids into four main clades. Clades 1ů3 include the various bodonid kinetoplastids. Trypanosomatids comprise the fourth clade. SSUrRNA analyses give vastly different and poorly supported positions for the root of the kinetoplastid tree, depending on the out-group and analysis method.
Trvalý link: http://hdl.handle.net/11104/0055023