The effect of HPMA copolymer-bound doxorubicin conjugates on the expression of genes involved on apoptosis signaling

0154657 - MBU-M 20020259 RIV US eng C - Konferenční příspěvek (zahraniční konf.)
Kovář, Lubomír - Ulbrich, Karel - Kovář, Marek - Strohalm, Jiří - Šťastný, Marek - Etrych, Tomáš - Říhová, Blanka
The effect of HPMA copolymer-bound doxorubicin conjugates on the expression of genes involved on apoptosis signaling.
International Symposium on Tumor Targeted Delivery Systems /2./. Maryland, 2002, s. 81-82.
[International Symposium on Tumor Targeted Delivery Systems /2./. Maryland (US), 22.09.2002-25.09.2002]
Grant CEP: GA ČR GA305/02/1425; GA AV ČR IAA4050201; GA AV ČR IBS5020101
Výzkumný záměr: CEZ:AV0Z5020903
Klíčová slova: hpma * copolymer-bound * doxorubicin
Kód oboru RIV: EE - Mikrobiologie, virologie

Doxorubicin (Dox), as one of the most commonly used cytostatic drug on oncology, does not show any specific accumulation within the tumor, and side-effects are limiting factors for the chemotherapy dosage.
Trvalý link: http://hdl.handle.net/11104/0052142