Stereology techniques in radiation biology

0142532 - FGU-C 20030067 RIV US eng J - Článek v odborném periodiku
Kubínová, Lucie - Mao, X. - Janáček, Jiří - Archambeau, J. O.
Stereology techniques in radiation biology.
Radiation Research. Roč. 160, č. 1 (2003), s. 110-119. ISSN 0033-7587. E-ISSN 1938-5404
Grant CEP: GA ČR GA304/01/0257
Grant ostatní: CZ-SK GA MŠk(CZ) KONTAKT 126/184
Výzkumný záměr: CEZ:AV0Z5011922
Klíčová slova: rat brain * radiation biology * stereology
Kód oboru RIV: EA - Morfologické obory a cytologie
Impakt faktor: 3.208, rok: 2003

This presentation reviews the methodology and format of using confocal microscopy and stereological methods to quantify tissue parameters, cell number, tissue volume and surface area, and vessel length. The description of stereological methods and their concepts is shown on an ongoing study of the dose response of the microvessels in proton irradiated hemibrain. Methods for estimating the brain volume and the brain cortex, total number of endothelial cells in cortical microvessels, length of cortical microvessels and the total surface area of cortical microvessel walls are presented step by step in a way understandable for readers with little mathematical background.
Trvalý link: http://hdl.handle.net/11104/0040233