Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of G(s)alpha protein and deranged signaling of adenylyl cyclase

0142529 - FGU-C 20030040 RIV NL eng J - Článek v odborném periodiku
Novotný, Jiří - Hrbasová, M. - Kolář, František - Svoboda, Petr
Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of G(s)alpha protein and deranged signaling of adenylyl cyclase.
Molecular and Cellular Biochemistry. Roč. 245, 1-2 (2003), s. 157-166. ISSN 0300-8177. E-ISSN 1573-4919
Grant CEP: GA ČR GA305/00/1660; GA ČR GA305/01/0279; GA MŠMT LN00A069
Výzkumný záměr: CEZ:AV0Z5011922
Klíčová slova: rat myocardium * pressure overload * cardiomegaly
Kód oboru RIV: CE - Biochemie
Impakt faktor: 1.763, rok: 2003

Pressure overload did not affect distribution of G proteins in immature myocardium, but considerably the content of the long isofom of Gs-alpha protein in hearts of adult rats. These hearts also exhibited markedly lower activity of adenylyl cyclase.
Trvalý link: http://hdl.handle.net/11104/0040230