Počet záznamů: 1
Altered myocardial Gs protein and adenylyl cyclase signaling in rats exposed to chronic hypoxia and normoxic recovery
- 1.0142526 - FGU-C 20030024 RIV US eng J - Článek v odborném periodiku
Hrbasová, M. - Novotný st., Jiří - Hejnová, Lucie - Kolář, František - Neckář, Jan - Svoboda, Petr
Altered myocardial Gs protein and adenylyl cyclase signaling in rats exposed to chronic hypoxia and normoxic recovery.
Journal of Applied Physiology. Roč. 94, č. 6 (2003), s. 2423-2432. ISSN 8750-7587. E-ISSN 1522-1601
Grant CEP: GA ČR GA305/00/1660; GA ČR GA305/01/0279; GA MŠMT LN00A026; GA MŠMT LN00A069
Výzkumný záměr: CEZ:AV0Z5011922
Klíčová slova: rat myocardium * beta-adrenoceptor * G protein
Kód oboru RIV: CE - Biochemie
Impakt faktor: 3.027, rok: 2003
Adaptation of rats to high-altitude hypoxia did not appreciably affect the number of beta-adrenergic receptors and the content of membrane-bound Gs-alpha protein, but it raised the amount of cytosolic Gs-alpha in right ventricles. Animals after a 5-week recovery still exhibited markedly elevated levels of cytosolic Gs-alpha and lower activity of adenylyl cyclase.
Trvalý link: http://hdl.handle.net/11104/0040227
Počet záznamů: 1