Počet záznamů: 1
Topological properties and spatial organization of villous capillaries in normal and diabetic placentas
- 1.0142340 - FGU-C 20020064 RIV CH eng J - Článek v odborném periodiku
Jirkovská, Marie - Kubínová, Lucie - Janáček, Jiří - Moravcová, M. - Krejčí, V. - Karen, Petr
Topological properties and spatial organization of villous capillaries in normal and diabetic placentas.
Journal of Vascular Research. Roč. 39, č. 3 (2002), s. 268-278. ISSN 1018-1172. E-ISSN 1423-0135
Grant CEP: GA ČR GA304/97/0420; GA ČR GA304/01/0257
Výzkumný záměr: CEZ:AV0Z5011922
Klíčová slova: diabetic placentas * vascular topology * confocal microscopy
Kód oboru RIV: EA - Morfologické obory a cytologie
Impakt faktor: 2.458, rok: 2002
Spatial arrangement and complexity of capillary bed of placental terminal villi were analyzed in 9 normal and 12 diabetic placentas. Specimens were taken by systematic random sampling. Series of thin optical sections of terminal villi and their developmental forms were recorded by the confocal microscope and used as initial data for 3-D visualization of the spatial arrangement of villous capillaries. It was found that the basic arrangement of villous capillaries is similar in both normal and diabetic placentas, nevertheless, the proportion of simple forms of capillary bed without redundant connections is significantly higher in normal placentas and the mean number of redundant connections per villus is significantly higher in diabetic placentas. It is concluded that both the longitudinal growth and branching of capillaries contribute to the increase of placental capillary bed in the late gestation and that the capillary bed of diabetic villi is more complicated due to more intense capillary branching.
Trvalý link: http://hdl.handle.net/11104/0040046
Počet záznamů: 1