Combination of Drugs Elevating Extracellular Adenosine with Granulocyte Colony-Stimulating Factor Promotes Granulopoietic Recovery in the Murine Bone Marrow after 5-Fluorouracil Treatment

0126459 - BFU-R 20013019 RIV CZ eng J - Článek v odborném periodiku
Hofer, Michal - Pospíšil, Milan - Weiterová, Lenka - Znojil, V. - Vácha, J. - Holá, Jiřina - Vacek, Antonín - Pipalová, Iva
Combination of Drugs Elevating Extracellular Adenosine with Granulocyte Colony-Stimulating Factor Promotes Granulopoietic Recovery in the Murine Bone Marrow after 5-Fluorouracil Treatment.
Physiological Research. Roč. 50, č. 5 (2001), s. 521-524. ISSN 0862-8408. E-ISSN 1802-9973
Grant CEP: GA ČR GA306/99/0027; GA AV ČR IBS5004009
Výzkumný záměr: CEZ:AV0Z5004920
Klíčová slova: 5-fluorouracil * granulopoiesis * extracellular adenosine
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 1.027, rok: 2001

Combined administration of drugs elevating extracellular adenosine, namely dipyridamole and adenosine monophosphate, together with granulocyte colony-stimulating factor was shown to enhance granulopoietic recovery in the bone marrow of mice treated with 5-fluorouracil. The results might have positive clinical impact. The adjunct use of drugs elevating extracellular adenosine might reduce the cost expenditure of therapy with granulocyte colony-stimulating factor
Trvalý link: http://hdl.handle.net/11104/0024688