Formin homology 2 domains occur in multiple contexts in angiosperms

0109762 - UEB-Q 20043104 RIV NL eng J - Článek v odborném periodiku
Cvrčková, F. - Novotný, M. - Pícková, Denisa - Žárský, Viktor
Formin homology 2 domains occur in multiple contexts in angiosperms.
[Formin homology 2 domains occur in multiple contexts in angiosperms.]
BMC Genomics. Roč. 5, č. 44 (2004), s. 1-18. ISSN 1471-2164. E-ISSN 1471-2164
Grant CEP: GA AV ČR KSK5052113
Klíčová slova: Formin * angiosperms * Arabidopsis
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 3.250, rok: 2004

Involvement of conservative molecular modules and cellular mechanisms in the widely diversified processes of eukaryotic cell morphogenesis leads to the intriguing question: how do similar proteins contribute to dissimilar morphogenetic outputs. Formins (FH2 proteins) play a central part in the control of actin organization and dynamics, providing a good example of evolutionarily versatile use of a conserved protein domain in the context of a variety of lineage-specific structural and signalling interactions. The plant-specific domain context of the conserved FH2 domain, as well as plant-specific features of the domain itself, may reflect distinct functional requirements in plant cells. The variability of formin structures found in plants far exceeds that known from both fungi and metazoans, suggesting a possible contribution of FH2 proteins in the evolution of the plant type of multicellularity.

Formin homology 2 domains occur in multiple contexts in angiosperms.
Trvalý link: http://hdl.handle.net/11104/0016870