Regulation of RGS3 function by 14-3-3 protein

0097681 - FGÚ 2008 US eng A - Abstrakt
Bouřa, Evžen - Obšil, Tomáš
Regulation of RGS3 function by 14-3-3 protein.
[Ovlivnění funkce RGS3 proteinem 14-3-3.]
Journal of Neurochemistry. Wiley. Roč. 102, Suppl.1 (2007), s. 272-272. ISSN 0022-3042. E-ISSN 1471-4159.
[Biennial meeting of the International Society for Neurochemistry /21./ and Annual meeting of the American Society for Neurochemistry /38./. 19.08.2007-24.08.2007, Cancun]
Grant CEP: GA ČR(CZ) GA204/06/0565; GA AV ČR(CZ) KJB500110601; GA MŠMT(CZ) LC554; GA ČR(CZ) GD203/05/H001
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: cpo1 * RGS * 14-3-3 * phosphorylation
Kód oboru RIV: BO - Biofyzika

Upon phosphorylation RGS3 binds 14-3-3 protein. This complex was prepared in vitro, and its stochiometry and stability was investigated. Using fluorescence spectroscopy the conformational changes induced by 14-3-3 binding were monitored

Po fosforylaci je protein RGS3 vázán 14-3-3 proteinem. Tento komplex byl pripraven in vitro. Zkoumána byla jeho stochiometrie, stabilita a pomoci fluorescencni spektroskopie byly sledovány konformační změny indukované 14-3-3 proteinem
Trvalý link: http://hdl.handle.net/11104/0156772