Hirtusneanoside, an Unsymmetrical Dimeric Tetrahydroxanthone from the Lichen Usnea hirta

0088908 - MBÚ 2008 RIV SIGLE US eng J - Článek v odborném periodiku
Řezanka, Tomáš - Sigler, Karel
Hirtusneanoside, an Unsymmetrical Dimeric Tetrahydroxanthone from the Lichen Usnea hirta.
[Hirtusneanosid, nesymetrický dimerní tetrahydroxanthon z lišejníku Usnea hirta.]
Journal of Natural Products. Roč. 70, - (2007), s. 1487-1491. ISSN 0163-3864. E-ISSN 1520-6025
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: usnea hirta * hirtusneanoside * gram-positive bacteria
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 2.551, rok: 2007

A novel O-deoxyglycoside of a dimeric tetrahydroxanthone, named hirtusneanoside, was isolated from the lichen Usnea hirta. Its structure, including the absolute configurations of the hydroxyl and methyl groups, and biphenyl moiety, was determined by means of extensive spectroscopic data (UV, IR, MS, CD, 1D and 2D NMR) and chemical degradation. Hirtusneanoside has a unique structure containing a tetrahydroxanthone dimer of O-glycoside with a L-rhamnopyranosyl unit, and showed growth inhibitory activities against Gram-positive bacteria

Z lišejníku Usnea hirta byl izolován hirtusneanoosid, O-deoxyglukosid dimerního tetrahydroxanthonu. Jeho struktura včetně absolutní konfigurace byla stanovena spektroskopicky a chemickou degradací. Hirtusneanosid je aktivní proti Gram-pozitivním bakteriím
Trvalý link: http://hdl.handle.net/11104/0150286