For a tree time can be slowed down: Analysis of proliferation capacity of tree cells

0050384 - GLÚ 2007 US eng A - Abstrakt
Flanary, B. E. - Kletetschka, Günther
For a tree time can be slowed down: Analysis of proliferation capacity of tree cells.
[Pro strom se čas může zpomalit: Analýza proliferační kapacity buněk stromu.]
Rejuvenation Research. Roč. 8, Supplement 1 (2005). ISSN 1549-1684. E-ISSN 1557-8577.
[Strategies for Engineered Negligible Senescence (SENS) /2./. 07.09.2005-11.09.2005, Cambridge]
Výzkumný záměr: CEZ:AV0Z30130516
Klíčová slova: telomers * telomerase * life span
Kód oboru RIV: EB - Genetika a molekulární biologie

In general, normal somatic cells proliferate with a finite replicative capacity and with each cell division, telomeres (the physical ends of linear chromosomes) progressively shorten until they reach a critical length, at which point the cells enter replicative senescence. Some cells maintain telomere length by the activation of the telomerase enzyme. The results from this study support the hypothesis that both increased telomere length and telomerase activity may directly/indirectly contribute to the increased life-span and longevity evident in long-lived pine trees (i.e., 2000-5000 year life-spans) compared to medium-lived (400-500 year life-span) and short-lived (100-200 year life-span) pine trees, as well as in P. longaeva with age.
Trvalý link: http://hdl.handle.net/11104/0140533