0048826 - ÚPT 2007 RIV GB eng J - Journal Article
Hering, D. - Somers, V. K. - Kára, T. - Kucharska, W. - Jurák, Pavel - Bieniaszewski, L. - Narkiewicz, K.
Sympathetic neural responses to smoking are age dependent.
[Reakce sympatického nervového systému na kouření je závislá na věku.]
Journal of Hypertension. Roč. 24, č. 4 (2006), s. 691-695. ISSN 0263-6352. E-ISSN 1473-5598
R&D Projects: GA ČR(CZ) GA102/05/0402
Institutional research plan: CEZ:AV0Z20650511
Keywords : sympathetic neural response * blood pressure * heart rate * smoking
Subject RIV: FS - Medical Facilities ; Equipment
Impact factor: 4.021, year: 2006

We tested the hypothesis that the sympathetic neural responses to smoking are age dependent. Results: Cigarette smoking increased heart rate in both middle-aged subjects and young subjects. In comparison to younger subjects, middle-aged smokers showed similar smoking-related increases in systolic blood pressure (SBP) [10 +/- 3 versus 12 +/- 2 mmHg, respectively, not significant (NS)]. Smoking decreased sympathetic nerve activity by 28 +/- 12% of baseline values (P < 0.01) in young subjects. However, muscle sympathetic nerve activity did not change significantly after smoking in middle-aged subjects (5 +/- 8%, NS), despite the increased blood pressures, which would be expected to inhibit sympathetic activity. By contrast, in young subjects, the heart rate increase (22 +/- 2 bpm) was greater than that seen in middle-aged subjects (13 +/- 2 bpm, P < 0.01). Conclusions: The autonomic responses to smoking are age dependent.

Práce potvrzuje hypotézu, že reakce sympatického nervového systému na kouření je závislá na věku. Nárůst krevního tlaku je shodný ve všech věkových skupinách, změna tepové frekvence a potlačení aktivity sympatiku je výraznější u mladých subjektů.
Permanent Link: http://hdl.handle.net/11104/0139367