Počet záznamů: 1

Importance of ERK1/2 in Regulation of Protein Translation during Oocyte Meiosis

SYSNO ASEP	0492350
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Importance of ERK1/2 in Regulation of Protein Translation during Oocyte Meiosis
Tvůrce(i)	Kalous, Jaroslav (UZFG-Y)_{RID, ORCID} Tětková, Anna (UZFG-Y)_ORCID Kubelka, Michal (UZFG-Y)_{RID, ORCID} Šušor, Andrej (UZFG-Y)_{RID, ORCID}
Číslo článku	698
Zdroj.dok.	International Journal of Molecular Sciences. - : MDPI Roč. 19, č. 3 (2018)
Poč.str.	21 s.
Jazyk dok.	eng - angličtina
Země vyd.	CH - Švýcarsko
Klíč. slova	ERK1/2 ; MAP kinase ; mTOR
Vědní obor RIV	EB - Genetika a molekulární biologie
Obor OECD	Reproductive biology (medical aspects to be 3)
CEP	GA15-22765S GA ČR - Grantová agentura ČR
	EF15_003/0000460 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy
Institucionální podpora	UZFG-Y - RVO:67985904
UT WOS	000428309800055
EID SCOPUS	85042787387
DOI	10.3390/ijms19030698
Anotace	Although the involvement of the extracellular signal-regulated kinases 1 and 2 (ERK1/2) pathway in the regulation of cytostatic factor (CSF) aktivity, as well as in microtubules organization during meiotic maturation of oocytes, has already been described in detail, rather less attention has been paid to the role of ERK1/2 in the regulation of mRNA translation. However, important data on the role of ERK1/2 in translation during oocyte meiosis have been documented. This review focuses on recent findings regarding the regulation of translation and the role of ERK1/2 in this process in the meiotic cycle of mammalian oocytes. The specific role of ERK1/2 in the regulation of mammalian target of rapamycin (mTOR), eukaryotic translation initiation factor 4E (eIF4E) and cytoplasmic polyadenylation element binding protein 1 (CPEB1) activity is addressed along with additional focus on the other key players involved in protein translation.
Pracoviště	Ústav živočišné fyziologie a genetiky
Kontakt	Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554
Rok sběru	2019

Počet záznamů: 1