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Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling

  1. 1.
    SYSNO0542896
    TitlePolymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
    Author(s) Sivák, Ladislav (MBU-M) RID
    Šubr, Vladimír (UMCH-V) [BIOMOL] RID, ORCID
    Kovářová, Jiřina (MBU-M)
    Dvořáková, Barbora (MBU-M) RID
    Šírová, Milada (MBU-M) RID, ORCID
    Říhová, Blanka (MBU-M) RID
    Randárová, Eva (UMCH-V) [BIOMOL] RID
    Kraus, Michal (MBU-M)
    Tomala, Jakub (MBU-M) RID, ORCID
    Studenovský, Martin (UMCH-V) [BIOMOL] RID, ORCID
    Vondráčková, Michaela (MBU-M)
    Sedláček, Radislav (UMG-J) [18] RID
    Makovický, Peter (UMG-J) [18]
    Fučíková, J. (CZ)
    Vošahlíková, Š. (CZ)
    Spíšek, R. (CZ)
    Kostka, Libor (UMCH-V) [BIOMOL] RID, ORCID
    Etrych, Tomáš (UMCH-V) [BIOMOL] RID, ORCID
    Kovář, Marek (MBU-M) RID, ORCID
    Corespondence/seniorKovář, Marek - Korespondující autor
    Source Title Journal of Controlled Release. Roč. 332, APR 10 2021 (2021), s. 563-580. - : Elsevier
    Document TypeČlánek v odborném periodiku
    Grant GA19-05649S GA ČR - Czech Science Foundation (CSF), CZ - Czech Republic
    LM2015040 GA MŠk - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    ED1.1.00/02.0109 GA MŠk - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    Institutional supportMBU-M - RVO:61388971 ; UMCH-V - RVO:61389013 ; UMG-J - RVO:68378050
    Languageeng
    CountryNL
    Keywords Ritonavir derivate * Polymer carrier * pH-controlled release * Antitumor activity * Proteasome inhibition * STAT3 signaling inhibition
    Cooperating institutions Univerzita Karlova v Praze (Czech Republic)
    Fakultní nemocnice Motol (Czech Republic)
    Sotio AS, Praha (Czech Republic)
    URLhttps://www.sciencedirect.com/science/article/pii/S0168365921001267
    Permanent Linkhttp://hdl.handle.net/11104/0320232
     
Number of the records: 1