Number of the records: 1

Fast decline of hematopoiesis and uncoupling protein 2 content in human liver after birth: location of the protein in Kupffer cells

SYSNO ASEP	0142145
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Ostatní články
Title	Fast decline of hematopoiesis and uncoupling protein 2 content in human liver after birth: location of the protein in Kupffer cells
Author(s)	Brauner, Petr (FGU-C) Nibbelink, M. (FR) Flachs, P. (CZ) Vítková, I. (CZ) Kopecký, P. (CZ) Mertelíková, Irena (FGU-C) Janderová, L. (CZ) Pénicaud, L. (FR) Casteilla, L. (FR) Plavka, R. (CZ) Kopecký, Jan (FGU-C)_{RID, ORCID}
Source Title	Pediatric Research. - : Springer - ISSN 0031-3998 Roč. 49, č. 3 (2001), s. 440-447
Number of pages	8 s.
Language	eng - English
Country	US - United States
Keywords	hepatic hematopoiesis ; uncoupling protein 2
Subject RIV	FB - Endocrinology, Diabetology, Metabolism, Nutrition
R&D Projects	LN00A079 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	NE4643 GA MZd - Ministry of Health (MZ)
CEZ	AV0Z5011922 - FGU-C
Annotation	Hepatic hematopoiesis is prominent during fetal life and declines around birth. We have investigated whether mitochondrial uncoupling protein 2 (UCP2) could be used as a marker of this process in human neonates. UCP2 expression was high prenatal and declined after birth, while being expressed in liver macrophages. UCP2 is a novel marker for the development of macrophages in developing liver.
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2002

Number of the records: 1