Number of the records: 1

Recent developments and applications of capillary and microchip electrophoresis in proteomic and peptidomic analyses

SYSNO ASEP	0458688
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Recent developments and applications of capillary and microchip electrophoresis in proteomic and peptidomic analyses
Author(s)	Štěpánová, Sille (UOCHB-X)_ORCID Kašička, Václav (UOCHB-X)_{RID, ORCID}
Source Title	Journal of Separation Science. - : Wiley - ISSN 1615-9306 Roč. 39, č. 1 (2016), s. 198-211
Number of pages	14 s.
Language	eng - English
Country	DE - Germany
Keywords	capillary electrophoresis ; mass spectrometry ; microchip electrophoresis ; peptidomics ; proteomics
Subject RIV	CB - Analytical Chemistry, Separation
R&D Projects	GA13-17224S GA ČR - Czech Science Foundation (CSF)
	GA15-01948S GA ČR - Czech Science Foundation (CSF)
Institutional support	UOCHB-X - RVO:61388963
UT WOS	000368876500016
EID SCOPUS	84956584150
DOI	10.1002/jssc.201500973
Annotation	This review presents recent developments and applications of capillary and microchip electromigration methods in proteomics and peptidomics. Sample preparation methods as well as instrumental innovations in the coupling of these advanced electromigration methods with mass spectrometry detection employed in proteomic and peptidomic analyses are presented. Interesting applications of various capillary electromigration methods in bottom-up as well as top-down proteomics, including investigation of post-translational modifications of proteins are described. In addition, several examples of the use of capillary electromigration methods combined with mass spectrometry detection in clinical proteomics and peptidomics are demonstrated.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2017

Number of the records: 1