Number of the records: 1  

Synergistic action of doxorubicin bound to the polymeric carrier based on N-(2-hydroxypropyl)methacrylamide copolymers through and amide or hydrazone bond

  1. 1.
    SYSNO ASEP0350325
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleSynergistic action of doxorubicin bound to the polymeric carrier based on N-(2-hydroxypropyl)methacrylamide copolymers through and amide or hydrazone bond
    Author(s) Říhová, Blanka (MBU-M) RID
    Etrych, Tomáš (UMCH-V) RID, ORCID
    Šírová, Milada (MBU-M) RID, ORCID
    Kovář, Lubomír (MBU-M)
    Hovorka, Ondřej (MBU-M)
    Kovář, Marek (MBU-M) RID, ORCID
    Benda, Aleš (UFCH-W) RID, ORCID
    Ulbrich, Karel (UMCH-V) RID
    Source TitleMolecular Pharmaceutics. - : American Chemical Society - ISSN 1543-8384
    Roč. 7, č. 4 (2010), s. 1027-1040
    Number of pages14 s.
    Languageeng - English
    CountryUS - United States
    Keywordshpma ; branched polymers ; EL4 T cell lymphoma
    Subject RIVEC - Immunology
    R&D ProjectsIAAX00500803 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    IAA400500806 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    1M0505 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    CEZAV0Z50200510 - MBU-M (2005-2011)
    AV0Z40500505 - UMCH-V (2005-2011)
    AV0Z40400503 - UFCH-W (2005-2011)
    UT WOS000280448100013
    DOI10.1021/mp100121g
    AnnotationThe cytostatic effects of polymeric conjugates based on N-(2-hydroxypropyl)methacrylamide copolymers (PHPMA) and containing doxorubicin bound through amide and hydrazone bonds (mixed conjugates) were compared with the cytostatic effects on monoconjugates containing drug bound through an amide or hydrazone bond
    WorkplaceInstitute of Microbiology
    ContactEliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
    Year of Publishing2011
Number of the records: 1  

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