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Cell proliferation on UV-excimer lamp modified and grafted polytetrafluoroethylene
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SYSNO ASEP 0101871 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Cell proliferation on UV-excimer lamp modified and grafted polytetrafluoroethylene Title Proliferace buněk na modifikovaném UV zářením z excimerové lampy a roubováním Author(s) Švorčík, V. (CZ)
Ročková, K. (CZ)
Ratajová, E. (CZ)
Heitz, J. (CZ)
Bauerle, D. (CZ)
Bačáková, L. (CZ)
Dvořánková, B. (CZ)
Hnatowicz, Vladimír (UJF-V) RIDSource Title Nuclear Instruments & Methods in Physics Research Section B. - : Elsevier - ISSN 0168-583X
Roč. 217, č. 2 (2004), s. 307-313Number of pages 7 s. Language eng - English Country CZ - Czech Republic Keywords polytetraflujoroethylene ; UV-beam modification in reactive atmosphere Subject RIV BG - Nuclear, Atomic and Molecular Physics, Colliders R&D Projects GA106/03/0514 GA ČR - Czech Science Foundation (CSF) IAA5011301 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z1048901 - UJF-V Annotation Polytetrafluoroethylene (PTFE) was modified by irradiation with 172 nm light from an UV-excimer lamp in reactive ammonia atmosphere. Then, the samples were exposed to aqueous solutions of amino acids (glycine, alanine and leucine). The samples were characterized by water contact angle measurement, UV-VIS spectroscopy and laser-induced fluorescence (LIF). The results indicate, that the amino acids are bound onto the polymer chain. The amount polytetrafluoroethylenu of incorporated amino acid is a decreasing function of its molecular size. By in vitro experiments it was shown that the incorporated amino acids support adhesion and proliferation of rat aortic smooth muscle cells and mouse embryonic 3T3 fibroblasts on the polymer surface. The maximum effect was observed for smallest molecule of glycine Workplace Nuclear Physics Institute Contact Markéta Sommerová, sommerova@ujf.cas.cz, Tel.: 266 173 228 Year of Publishing 2005
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