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Characterization of the morphological nature of hollow spray dried dispersion particles using X-ray submicron-computed tomography
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SYSNO ASEP 0561028 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Characterization of the morphological nature of hollow spray dried dispersion particles using X-ray submicron-computed tomography Author(s) Gamble, J.F. (GB)
Tobyn, M. (GB)
Zhang, S. (US)
Zhu, A. (US)
Šalplachta, J. (CZ)
Matula, J. (CZ)
Zikmund, T. (CZ)
Kaiser, J. (CZ)
Oberta, Peter (FZU-D) RID, ORCIDNumber of authors 9 Article number 40 Source Title AAPS PharmSciTech. - : Springer - ISSN 1530-9932
Roč. 23, č. 1 (2022)Number of pages 7 s. Language eng - English Country US - United States Keywords spray drying ; materials science ; morphology ; physical characterization ; solid dispersion Subject RIV CE - Biochemistry OECD category Medical laboratory technology (including laboratory samples analysis Method of publishing Limited access Institutional support FZU-D - RVO:68378271 UT WOS 000735427900003 EID SCOPUS 85122045188 DOI 10.1208/s12249-021-02184-7 Annotation One of the many applications of spray drying is to produce amorphous systems enabling improved dissolution profiles for poorly soluble pharmaceutical ingredients (API). Spray drying involves the rapid drying of an atomized feed solution consisting of organic and/or aqueous solvent(s) containing an API plus any additional components, such as polymers, used to deliver an amorphous system (1–4).
Workplace Institute of Physics Contact Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Year of Publishing 2023 Electronic address https://doi.org/10.1208/s12249-021-02184-7
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