Number of the records: 1
Characterization of the morphological nature of hollow spray dried dispersion particles using X-ray submicron-computed tomography
- 1.0561028 - FZÚ 2023 RIV US eng J - Journal Article
Gamble, J.F. - Tobyn, M. - Zhang, S. - Zhu, A. - Šalplachta, J. - Matula, J. - Zikmund, T. - Kaiser, J. - Oberta, Peter
Characterization of the morphological nature of hollow spray dried dispersion particles using X-ray submicron-computed tomography.
AAPS PharmSciTech. Roč. 23, č. 1 (2022), č. článku 40. ISSN 1530-9932. E-ISSN 1530-9932
Institutional support: RVO:68378271
Keywords : spray drying * materials science * morphology * physical characterization * solid dispersion
OECD category: Medical laboratory technology (including laboratory samples analysis
Impact factor: 3.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1208/s12249-021-02184-7
One of the many applications of spray drying is to produce amorphous systems enabling improved dissolution profiles for poorly soluble pharmaceutical ingredients (API). Spray drying involves the rapid drying of an atomized feed solution consisting of organic and/or aqueous solvent(s) containing an API plus any additional components, such as polymers, used to deliver an amorphous system (1–4).
Permanent Link: https://hdl.handle.net/11104/0333785
Number of the records: 1