Growth/differentiation factor-I5 is an abundant cytokine in human seminal plasma

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SYSNO ASEP	0353806
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Growth/differentiation factor-I5 is an abundant cytokine in human seminal plasma
Author(s)	Souček, Karel (BFU-R)_{RID, ORCID} Slabáková, Eva (BFU-R)_{RID, ORCID} Ovesná, P. (CZ) Malenovská, A. (CZ) Kozubík, Alois (BFU-R)_{RID, ORCID} Hampl, Aleš (UEM-P)
Number of authors	6
Source Title	Human Reproduction - ISSN 0268-1161 Roč. 25, č. 12 (2010), s. 2962-2971
Number of pages	10 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	seminal plasma ; growth/differentiation factor-15 (GDF-15/MIC-1) ; FOXP3
Subject RIV	BO - Biophysics
R&D Projects	NS9600 GA MZd - Ministry of Health (MZ)
CEZ	AV0Z50040507 - BFU-R (2005-2011)
	AV0Z50040702 - BFU-R (2007-2013)
	AV0Z50390703 - UEM-P (2007-2013)
UT WOS	000284637500008
DOI	10.1093/humrep/deq264
Annotation	Transforming growth factor-beta cytokines have various biological effects in female reproductive tissue, including modulation of inflammatory response and induction of imune tolerance to seminal antigens in the reproductive tract. However, no studies have analyzed the presence of growth/differentiation factor-15 (GDF-15/macrophage inhibitory cytokine-1) in seminal fluid or demonstrated the quantity and form of GDF-15, its possible role or the relationship between its concentration and semen quality.
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2011

Number of the records: 1