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Growth/differentiation factor-I5 is an abundant cytokine in human seminal plasma

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    0353806 - BFÚ 2011 RIV GB eng J - Journal Article
    Souček, Karel - Slabáková, Eva - Ovesná, P. - Malenovská, A. - Kozubík, Alois - Hampl, Aleš
    Growth/differentiation factor-I5 is an abundant cytokine in human seminal plasma.
    Human Reproduction. Roč. 25, č. 12 (2010), s. 2962-2971. ISSN 0268-1161. E-ISSN 1460-2350
    R&D Projects: GA MZd NS9600
    Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702; CEZ:AV0Z50390703
    Keywords : seminal plasma * growth/differentiation factor-15 (GDF-15/MIC-1) * FOXP3
    Subject RIV: BO - Biophysics
    Impact factor: 4.357, year: 2010

    Transforming growth factor-beta cytokines have various biological effects in female reproductive tissue, including modulation of inflammatory response and induction of imune tolerance to seminal antigens in the reproductive tract. However, no studies have analyzed the presence of growth/differentiation factor-15 (GDF-15/macrophage inhibitory cytokine-1) in seminal fluid or demonstrated the quantity and form of GDF-15, its possible role or the relationship between its concentration and semen quality.
    Permanent Link: http://hdl.handle.net/11104/0192947

     
     
Number of the records: 1  

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