Number of the records: 1
G4Killer web application: a tool to design G-quadruplex mutations
- 1.0539893 - BFÚ 2021 RIV GB eng J - Journal Article
Brázda, Václav - Kolomaznik, J. - Mergny, Jean-Louis - Šťastný, J.
G4Killer web application: a tool to design G-quadruplex mutations.
Bioinformatics. Roč. 36, č. 10 (2020), s. 3246-3247. ISSN 1367-4803. E-ISSN 1460-2059
R&D Projects: GA ČR(CZ) GA18-15548S; GA MŠMT EF15_003/0000477
Institutional support: RVO:68081707
Keywords : G4Killer * web application * G-quadruplex mutations
OECD category: Biochemistry and molecular biology
Impact factor: 6.937, year: 2020
Method of publishing: Open access
https://academic.oup.com/bioinformatics/article/36/10/3246/5716328
Motivation: G-quadruplexes (G4) are important regulatory non-B DNA structures with therapeutic potential. A tool for rational design of mutations leading to decreased propensity for G4 formation should be useful in studying G4 functions. Although tools exist for G4 prediction, no easily accessible tool for the rational design of G4 mutations has been available.
Permanent Link: http://hdl.handle.net/11104/0317588
Number of the records: 1