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Translational Research in Serious Human Diseases
- 1.0536618 - ÚŽFG 2021 RIV CZ eng M - Monography Chapter
Miltrová, Veronika - Kupcová Skalníková, Helena
Cytokines in malignant melanoma.
Translational Research in Serious Human Diseases. Praha: Academia, 2020 - (Kello, M.; Strnadel, J.; Klempir, J.; Roth, J.; Myslivcová-Fučíková, A.; Hansíková, H.; Kozák, I.), s. 208-217. ISBN 978-80-200-3158-7
R&D Projects: GA MŠMT(CZ) LO1609; GA MŠMT(CZ) EF16_019/0000785
Institutional support: RVO:67985904
Keywords : cytokines * melanoma * regression
OECD category: Oncology
Cutaneous melanoma is a malignant skin disease. Melanoma is a highly immunogenic tumour and patient‘ s own immunity plays an important role in the control of melanoma growth and spreading. Cytokines are small secreted proteins that are not only key regulators of immune reactions but also mediators of intercellular interactions in the melanoma microenvironment. Cytokines have diagnostic, prognostic and therapeutic potential, however additional studies are required to fully understand their regulatory networks. A pig MeLiM model has a potential to help our understanding of immune reactions in melanoma regression.
Permanent Link: http://hdl.handle.net/11104/0314367
Number of the records: 1