Self-assembly and nanostructure of poly(vinyl alcohol)-graft-poly(methyl methacrylate) amphiphilic nanoparticles

0505871 - ÚMCH 2020 RIV US eng J - Journal Article
Halamish, H. M. - Trousil, Jiří - Rak, D. - Knudsen, K. D. - Pavlova, Ewa - Nyström, B. - Štěpánek, Petr - Sosnik, A.
Self-assembly and nanostructure of poly(vinyl alcohol)-graft-poly(methyl methacrylate) amphiphilic nanoparticles.
Journal of Colloid and Interface Science. Roč. 553, 1 October (2019), s. 512-523. ISSN 0021-9797. E-ISSN 1095-7103
R&D Projects: GA ČR(CZ) GA17-07164S; GA ČR(CZ) GA17-09998S; GA TA ČR(CZ) TE01020118
Grant - others:AV ČR(CZ) ISR-17-21
Program: Bilaterální spolupráce
Institutional support: RVO:61389013
Keywords : poly(vinyl alcohol)-poly(methyl methacrylate) amphiphilic nanoparticles * polymer self-assembly * asymmetric flow field-flow fractionation (A4F)
OECD category: Polymer science
Impact factor: 7.489, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0021979719307209?via%3Dihub

Poly(vinyl alcohol)-g-poly(methyl methacrylate) (PVA-g-PMMA) amphiphilic copolymers self-assemble to form multi-micellar colloidal systems. A PVA-g-PMMA copolymer containing 16–17% w/w of PMMA was synthesized by the free radical graft polymerization of methyl methacrylate on a PVA backbone by utilizing cerium(IV) ammonium nitrate as initiator and tetramethylethylenediamine (TEMED) as initiation activator. The aggregation behavior of the copolymer in water was comprehensively characterized by dynamic light scattering (DLS) and static light scattering (SLS), small angle neutron scattering (SANS), asymmetrical flow field-flow fractionation (A4F) and transmission electron microscopy (TEM). The colloidal stability before and after non-covalent crosslinking of PVA domains with boric acid was assessed by DLS. Finally, nanoparticles were nano spray-dried. This copolymer self-assembles in water to form a complex nanostructure of low aggregation number particles (ca. 12–15 nm in diameter) that aggregate into larger ones with size ca. 60–80 nm, as determined by SANS and TEM. In addition, boric acid-crosslinking preserves the nanoparticle size, while conferring full physical stability under extreme dilution conditions. Nano spray-drying consolidates the crosslnking and enables the production of a dry flowing powder that upon re-dispersion in water regenerates the nanoparticles without major size changes.
Permanent Link: http://hdl.handle.net/11104/0297391