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Hexahistidine-based tag for capillary electrophoresis-mass spektrometry analysis of oligosaccharides and N-linked glycans
- 1.0499016 - ÚIACH 2019 RIV CZ eng C - Conference Paper (international conference)
Partyka, Jan - Křenková, Jana - Čmelík, Richard - Foret, František
Hexahistidine-based tag for capillary electrophoresis-mass spektrometry analysis of oligosaccharides and N-linked glycans.
CECE 2018. 15th International Interdisciplinary Meeting on Bioanalysis. Brno: Ústav analytické chemie AV ČR, v. v. i., 2018 - (Foret, F.; Křenková, J.; Drobníková, I.; Klepárník, K.; Přikryl, J.), s. 239-241. ISBN 978-80-904959-5-1.
[CECE 2018. International Interdisciplinary Meeting on Bioanalysis /15./. Brno (CZ), 15.10.2018-17.10.2018]
R&D Projects: GA ČR(CZ) GJ16-09283Y; GA ČR(CZ) GBP206/12/G014
Institutional support: RVO:68081715
Keywords : CE-MS analysis * oligosaccharides * amino acids * peptides
OECD category: Analytical chemistry
http://www.ce-ce.org/user_uploads/program/CECE%202018%20Proceedings_WOS.pdf
Various basic amino acids and peptides were studied as an alternative labels for capillary electrophoresis-mass spectrometry analysis of oligosaccharides. The hexahistidine-based label with big number of positive charges allowed to use effective and sensitive CE-MS analysis in positive ion mode both neutral and acidic glycans.
Permanent Link: http://hdl.handle.net/11104/0291305
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