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Oxidative stress and chromosomal aberrations in an environmentally exposed population
- 1.0358218 - ÚEM 2011 RIV NL eng J - Journal Article
Rössner ml., Pavel - Rössnerová, Andrea - Šrám, Radim
Oxidative stress and chromosomal aberrations in an environmentally exposed population.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. Roč. 707, 1-2 (2011), s. 34-41. ISSN 0027-5107
R&D Projects: GA MŽP(CZ) SP/1B3/8/08
Institutional research plan: CEZ:AV0Z50390512
Keywords : air pollution * oxidative stress * chromosomal aberrations
Subject RIV: DN - Health Impact of the Environment Quality
Impact factor: 2.850, year: 2011
The effect of seasonal variability of environmental air pollutants (c-PAHs and particulate matter PM2.5) on oxidative stress and cytogenetic biomarkes in a group of city policement from Prague was investigated. No significant difference between the two seasons (February and May 2007) for any biomarkers of oxidative stress (8-oxodG, 15-F2t-IsoP) or any cytogenetic parameter (genomic frequency of translocations – FG/100; % AB.C.; or the number of acentric fragments – ace) was observed. The effects of air pollution on all subjects regardless of the season was also studied. In summary, the results indicate that the exposure to environmental pollutants affects urinary excretion of 8-oxodG, lipid peroxidation and the frequency of chromosomal aberrations.
Permanent Link: http://hdl.handle.net/11104/0196315
Number of the records: 1