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New predictive model for monitoring bone remodeling
- 1.0353375 - ÚT 2011 RIV US eng J - Journal Article
Bougherara, H. - Klika, Václav - Maršík, František - Mařík, I. - Yahia, L.H.
New predictive model for monitoring bone remodeling.
Journal of Biomedical Materials Research. Part A. 95A, č. 1 (2010), s. 9-24. ISSN 1549-3296. E-ISSN 1552-4965
R&D Projects: GA ČR GA106/03/1073; GA ČR(CZ) GA106/03/0958
Institutional research plan: CEZ:AV0Z20760514
Keywords : bone remodeling * open system thermodynamics * bone biochemistry
Subject RIV: BJ - Thermodynamics
Impact factor: 3.044, year: 2010
The model is based on chemical kinetics and irreversible thermodynamic principles, in which bone is considered as a self-organizing system that exchanges matter, energy and entropy with its surroundings. The current model suggested that bone remodeling was a dynamic process which was driven by mechanical loading, metabolic factors and other external contributions. Furthermore, results of virtual computations of bone density in a composite femur showed the development of a dense cortical bone around the medullary canal and a dense trabeculae bone between the femoral head and the calcar region of the medial cortex due to compressive stresses.
Permanent Link: http://hdl.handle.net/11104/0192642
Number of the records: 1