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NK cell-mediated cytotoxicity modulation by A2 adenosine receptor agonist in different mammalian species
- 1.0335164 - MBÚ 2010 RIV CZ eng J - Journal Article
Kuldová, Markéta - Svoboda, Jan - Kovářů, F. - Vannucci, Luca - Kovářů, H. - Fišerová, Anna
NK cell-mediated cytotoxicity modulation by A2 adenosine receptor agonist in different mammalian species.
Folia Microbiologica. Roč. 54, č. 4 (2009), s. 364-368. ISSN 0015-5632. E-ISSN 1874-9356
R&D Projects: GA AV ČR KJB500200614; GA AV ČR IAA601680801
Institutional research plan: CEZ:AV0Z50200510
Keywords : CYTOKINE PRODUCTION * TISSUE-DAMAGE * KILLER-CELLS
Subject RIV: EC - Immunology
Impact factor: 0.978, year: 2009
We evaluated the influence of A2 adenosine receptor (A2AR) agonist on cytotoxic-cell response comparing human with other mammalian species (rodents, pigs, goats), both in healthy and in cancer conditions. The A2AR agonist developed dose-dependent inhibition of the cytotoxic activity of immune effector cells in all studied species
Permanent Link: http://hdl.handle.net/11104/0179706
Number of the records: 1