The Effect of Activation of Mammalian Oocytes on Remodeling of Donor Nuclei after Nuclear Transfer

0213512 - UZFG-Y 20023128 RIV US eng J - Journal Article
Motlík, Jan - Alberio, R. - Zakhartchenko, V. - Stojkovic, M. - Kubelka, Michal - Wolf, E.
The Effect of Activation of Mammalian Oocytes on Remodeling of Donor Nuclei after Nuclear Transfer.
Cloning and Stem Cells. Roč. 4, č. 3 (2002), s. 245-252. ISSN 1536-2302
R&D Projects: GA MŠMT LN00A065; GA AV ČR KSK5052113
Keywords : nuclear transfer
Subject RIV: EB - Genetics ; Molecular Biology

Activation of bovine oocytes by experimental procedures that closely mimic normal fertilization is essential both for intracytoplasmic sperm injection and for nuclear transfer (NT). Therefore, with the goal of producing haploid activated oocytes, we evaluated whether butyrolactone I and bohemine, either alone or in combination with ionomycin, are able to activate young matured mammalian oocytes.
Permanent Link: http://hdl.handle.net/11104/0109048