0195036 - UOCHB-X 20030344 RIV DE eng J - Journal Article
Gómez-Coca, R. G. - Holý, Antonín - Vilaplana, R. A. - González-Vílchez, F. - Sigel, H.
Solution structures of binary and ternary metal ion complexes of 9-(5-phosphonopentyl)adenine (3'-deoxa-PEEA). A nucleotide analogue related ti the antivirally active 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).
European Journal of Inorganic Chemistry. - (2003), s. 2937-2947. ISSN 1434-1948. E-ISSN 1099-0682
R&D Projects: GA AV ČR IBS4055109; GA MŠMT OC D20.002
Institutional research plan: CEZ:AV0Z4055905
Keywords : antiviral agents * chelates * nucleotides
Subject RIV: CC - Organic Chemistry
Impact factor: 2.482, year: 2003

The acidity constants of the twofold protonated acyclic 9-(5-phosphonopentyl)adenine, complexes with the metal ions have been determined. For the complexes a stability increase in observed which is due to macrochelate formation with the adenine residue, i.e. most likely with N7.
Permanent Link: http://hdl.handle.net/11104/0090703