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Synthetic macromolecular drug carriers: biodistribution of poly[N-2-hydroxypropyl)methacrylamide] and its accumulation in solid rat tumors

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    0188310 - UMCH-V 20010083 RIV US eng C - Conference Paper (international conference)
    Peschke, P. - Kissel, M. - Šubr, Vladimír - Ulbrich, Karel - Schuhmacher, J. - Debus, J. - Friedrich, E.
    Synthetic macromolecular drug carriers: biodistribution of poly[N-2-hydroxypropyl)methacrylamide] and its accumulation in solid rat tumors.
    Proceedings. San Diego: Controlled Release Society, 2001, s. No.7150.
    [International Symposium on Controlled Release of Bioactive Materials. San Diego (US), 23.06.2001-27.06.2001]
    R&D Projects: GA ČR GV307/96/K226; GA AV ČR KSK4055109
    Institutional research plan: CEZ:AV0Z4050913
    Subject RIV: ED - Physiology

    To further exploire the in vivo disposition characteristics of poly[N-(2-hydroxypropyl)methacrylamide] (pHPMA), we evaluated the pharmacokinetic and biodistribution in organs of 6 polymers differing in molecular weight using a rat prostate tumor model.
    Permanent Link: http://hdl.handle.net/11104/0084273

     
     

Number of the records: 1  

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