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Learning Deficits in Aged Rats Related to Decrease in Extracellular Volume and Loss of Diffusion Anisotropy in Hippocampus
- 1.0173562 - UEM-P 20023003 RIV US eng J - Journal Article
Syková, Eva - Mazel, Tomáš - Hasenohrl, R. U. - Harvey, A. R. - Šimonová, Zuzana - Mulders, W. H. A. M. - Huston, J. P.
Learning Deficits in Aged Rats Related to Decrease in Extracellular Volume and Loss of Diffusion Anisotropy in Hippocampus.
Hippocampus. Roč. 12, - (2002), s. 469-479. ISSN 1050-9631. E-ISSN 1098-1063
R&D Projects: GA MŠMT LN00A065; GA ČR GV309/97/K048; GA ČR GA309/99/0657
Grant - others:AU(XC) NHMRC
Institutional research plan: CEZ:AV0Z5039906; CEZ:MSM 111300004
Keywords : aging * glycoproteins
Subject RIV: FH - Neurology
Impact factor: 3.421, year: 2002
The degree of impaired maze performance of old rats correlates, firstly, with decrease in ECS volume, loss of diffusion anisotropy in hippocampus, and degree of astrogliosis, and secondly, with disorganization of the astrocytic processes and reduction of hippocampal ECS matrix molecules.
Permanent Link: http://hdl.handle.net/11104/0070594
Number of the records: 1