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Heritability and tissue specificity of expression quantitative trait loci

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    0043460 - FGÚ 2007 RIV US eng J - Journal Article
    Petretto, E. - Mangion, J. - Dickens, N. J. - Cook, S.A. - Kumaran, M. K. - Lu, H. - Fischer, J. - Maatz, H. - Křen, Vladimír - Pravenec, Michal - Hubner, N. - Aitman, T. J.
    Heritability and tissue specificity of expression quantitative trait loci.
    [Heritabilita a tkáňová specificita expresních lokusů kvantitativních znaků.]
    PLoS Genetics. Roč. 2, č. 10 (2006), s. 1625-1633. ISSN 1553-7390
    R&D Projects: GA MŠMT(CZ) 1M0520; GA ČR(CZ) GA301/06/0028; GA ČR(CZ) GA301/04/0390
    Grant - others:HHMI(US) 55005624
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : expression QTL * heritability * tissue specificity
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 7.671, year: 2006

    We described the influence of heritability and allelic effect of the quantitative trait locus on detection of cis- and trans-acting eQTLs and discuss how these factors operate in a tissue-specific context

    Popsali jsme vliv heritability a alelických efektů lokusů kvantitativních znaků na detekci cis- a trans-regulovaných eQTL a posoudili, jak tyto faktory působí v tkáňově specifickém kontextu
    Permanent Link: http://hdl.handle.net/11104/0136443

     
     
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