Počet záznamů: 1

Structural basis for DNA recognition by FOXO proteins

  1. 1.
    0369959 - FGU-C 2012 RIV NL eng J - Článek v odborném periodiku
    Obšil, T. - Obšilová, Veronika
    Structural basis for DNA recognition by FOXO proteins.
    Biochimica Et Biophysica Acta-Molecular Cell Research. Roč. 1813, č. 11 (2011), s. 1946-1953 ISSN 0167-4889
    Grant CEP: GA AV ČR(CZ) IAA501110801; GA ČR(CZ) GAP207/11/0455; GA MŠk(CZ) LC554
    Grant ostatní:GA ČR(CZ) GAP305/11/0708
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: forkhead * FOXO * DNA * structure * DNA recognition
    Kód oboru RIV: CE - Biochemie
    Impakt faktor: 5.538, rok: 2011

    The FOXO forkhead transcription factors are involved in metabolism control, cell survival, cellular proliferation DNA damage repair response, and stress resistance. The aim of this review is to summarize the recent structural characterization of FOXO proteins, the mechanisms of DNA recognition and the role of posttranslational modifications in the regulation of FOXO DNA-binding properties
    Trvalý link: http://hdl.handle.net/11104/0203896