Počet záznamů: 1

Enantioselective Epoxide Ring Opening Catalyzed by Bis(tetrahydroisoquinoline) N,N’-Dioxides

  1. 1.
    0369758 - UOCHB-X 2012 RIV CZ eng J - Článek v odborném periodiku
    Kadlčíková, A. - Vlašná, K. - Kotora, Martin
    Enantioselective Epoxide Ring Opening Catalyzed by Bis(tetrahydroisoquinoline) N,N’-Dioxides.
    Collection of Czechoslovak Chemical Communications. Roč. 76, č. 5 (2011), s. 415-422 ISSN 0010-0765
    Grant ostatní: GA MŠk(CZ) LC06070; GA ČR(CZ) GAP207/11/0587
    Výzkumný záměr: CEZ:AV0Z40550506
    Klíčová slova: asymmetric catalysis * silanes * N ligands * enantioselectivity
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 1.283, rok: 2011

    Four bis(tetrahydroisoquinoline) N,N′-dioxides were used as catalysts for the epoxide ring opening with tetrachlorosilane under various conditions. A strong solvent effect on asymmetric induction was observed for each of the used catalysts. The highest achieved asymmetric induction for the opening of meso-stilbene oxide was 69% ee. Regarding the cycloalkene oxides, 56% ee was obtained in the reaction with cyclooctene oxide.
    Trvalý link: http://hdl.handle.net/11104/0203751