Počet záznamů: 1

Generation of hydrogen peroxide in the developing rat heart: the role of elastin metabolism

  1. 1.
    0369506 - FGU-C 2012 RIV US eng J - Článek v odborném periodiku
    Wilhelm, J. - Ošťádalová, Ivana - Vytášek, R. - Vajner, L.
    Generation of hydrogen peroxide in the developing rat heart: the role of elastin metabolism.
    Molecular and Cellular Biochemistry. Roč. 358, 1-2 (2011), s. 215-220 ISSN 0300-8177
    Grant CEP: GA MŠk(CZ) 1M0510
    Grant ostatní: GA ČR(CZ) GAP303/11/0298
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: rat heart * ontogenetic development * hydrogen peroxide * elastin * fluorescence
    Kód oboru RIV: FA - Kardiovaskulární nemoci vč. kardiochirurgie
    Impakt faktor: 2.057, rok: 2011

    The production of hydrogen peroxide (H2O2) during development (starting from day 21 after conception up to adulthood) of the rat heart was studied. H2O2, that modifies elastin, is produced by lysyl oxidase since day 4 up to day 15 only extracellularly, later on even intracellular production was observed. The specific inhibitor of lysyl oxadase abolished production of H2O2
    Trvalý link: http://hdl.handle.net/11104/0203554