Počet záznamů: 1

Common and distinct roles of juvenile hormone signaling genes in metamorphosis of holometabolous and hemimetabolous insect

  1. 1.
    0369386 - BC-A 2012 RIV US eng J - Článek v odborném periodiku
    Konopová, Barbora - Smýkal, V. - Jindra, Marek
    Common and distinct roles of juvenile hormone signaling genes in metamorphosis of holometabolous and hemimetabolous insect.
    PLoS ONE. Roč. 6, č. 12 (2011), e28728 E-ISSN 1932-6203
    Grant CEP: GA ČR(CZ) GA204/07/1032; GA ČR(CZ) GD204/09/H058; GA AV ČR IAA500960906
    Výzkumný záměr: CEZ:AV0Z50070508
    Klíčová slova: juvenile hormone
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 4.092, rok: 2011

    Juvenile hormone (JH) was so named for its capacity to block metamorphosis of larvae to adults. Only when larvae attain an appropriate stage, a halt of JH secretion permits metamorphosis. JH acts through its receptor, the Methoprene-tolerant (Met) protein, whose target gene Kr-h1 blocks metamorphosis. In this study we discovered that the same molecular mechanism of JH action operates in evolutionarily very distant insects with complete (holometaboly) and incomplete (hemimetaboly) metamorphosis, and is therefore universal to insects. The common role of Kr-h1 in suppressing metamorphosis supports hypotheses on common evolutionary origin of larval and pupal stages in the two types of metamorphosis.
    Trvalý link: http://hdl.handle.net/11104/0203462