Počet záznamů: 1

N9-Substituted N(6)-[(3-methylbut-2-en-1-yl)amino]purine derivatives and their biological activity in selected cytokinin bioassays

  1. 1.
    0368655 - UEB-Q 2012 RIV GB eng J - Článek v odborném periodiku
    Mik, V. - Szüčová, Lucie - Spíchal, Lukáš - Plíhal, O. - Nisler, Jaroslav - Zahajská, L. - Doležal, Karel - Strnad, Miroslav
    N9-Substituted N(6)-[(3-methylbut-2-en-1-yl)amino]purine derivatives and their biological activity in selected cytokinin bioassays.
    Bioorganic & Medicinal Chemistry. Roč. 19, č. 23 (2011), s. 7244-7251 ISSN 0968-0896
    Grant CEP: GA MŠk ED0007/01/01; GA ČR GA522/09/1576
    Klíčová slova: N6-[(3-Methylbut-2-en-1-yl)amino]purine * Isopentenyladenine derivatives * N9-Substituted derivatives * Cytokinins * Cytokinin receptors
    Kód oboru RIV: EF - Botanika
    Impakt faktor: 2.921, rok: 2011

    Rational design is one of the latest ways how to evaluate particular activity of signal molecules, for example cytokinin derivatives. A series of N(6)-[(3-methylbut-2-en-1-yl)amino]purine (iP) derivatives specifically substituted at the N9 atom of purine moiety by tetrahydropyran-2-yl, ethoxyethyl, and C2-C4 alkyl chains terminated by various functional groups were prepared. The reason for this rational design was to reveal the relationship between specific substitution at the N9 atom of purine moiety of iP and cytokinin activity of the prepared compounds. The synthesis was carried out either via 6-chloro-9-substituted intermediates prepared originally from 6-chloropurine, or by a direct alkylation of N9 atom of N(6)-[(3-methylbut-2-en-1-yl)amino]purine.
    Trvalý link: http://hdl.handle.net/11104/0202945