Počet záznamů: 1

Nucleobase modification as redox DNA labelling for electrochemical detection

  1. 1.
    0368112 - UOCHB-X 2012 RIV GB eng J - Článek v odborném periodiku
    Hocek, Michal - Fojta, Miroslav
    Nucleobase modification as redox DNA labelling for electrochemical detection.
    Chemical Society Reviews. Roč. 40, č. 12 (2011), s. 5802-5814 ISSN 0306-0012
    Grant CEP: GA MŠk(CZ) LC06035; GA MŠk LC512; GA AV ČR(CZ) IAA400040901; GA ČR GA203/09/0317
    Výzkumný záměr: CEZ:AV0Z40550506; CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: nucleotides * oligonucleotides * DNA * electrochemistry * redox labeling
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 28.760, rok: 2011

    Basic aspects of DNA electrochemistry with a strong focus on the use of modified nucleobases as redox probes for electrochemical bioanalysis are reviewed. Intrinsic electrochemical properties of nucleobases in combination with artificial redox-active nucleobase modifications are frequently applied in this field. Synthetic approaches to base-modified nucleic acids are briefly summarized and their applications in redox labelling are discussed.
    Trvalý link: http://hdl.handle.net/11104/0202554