Počet záznamů: 1

Oxime reactivators and their in vivo and in vitro effects on nicotinic receptors

  1. 1.
    0367444 - FGU-C 2012 RIV CZ eng J - Článek v odborném periodiku
    Soukup, O. - Krůšek, Jan - Kaniaková, Martina - Kumar, U. K. - Oz, M. - Jun, D. - Fusek, J. - Kuča, K. - Tobin, G.
    Oxime reactivators and their in vivo and in vitro effects on nicotinic receptors.
    Physiological Research. Roč. 60, č. 4 (2011), s. 679-686 ISSN 0862-8408
    Grant CEP: GA ČR(CZ) GA202/09/0806; GA MŠk(CZ) LC554
    Grant ostatní: GA ČR(CZ) GAP303/11/1907
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: organophosphates * patch-clamp * nicotinic receptors * reactivator * isometric muscle contraction * TE671 cells
    Kód oboru RIV: FR - Farmakologie a lékárnická chemie
    Impakt faktor: 1.555, rok: 2011

    Antinicotinic properties of oximes reactivators were examined by in-vitro and in-vivo methods. We found that oximes (HI-6, obidoxime, K027 and K203) antagonize the nicotinic receptors of both adult and embryonic form with different potency
    Trvalý link: http://hdl.handle.net/11104/0202135