Počet záznamů: 1

Molecular characterization of the iron binding protein ferritin in Eisenia andrei earthworms

  1. 1.
    0366799 - MBU-M 2012 RIV NL eng J - Článek v odborném periodiku
    Procházková, Petra - Dvořák, Jiří - Šilerová, Marcela - Roubalová, Radka - Škanta, František - Halada, Petr - Bilej, Martin
    Molecular characterization of the iron binding protein ferritin in Eisenia andrei earthworms.
    Gene. Roč. 485, č. 2 (2011), s. 73-80 ISSN 0378-1119
    Grant CEP: GA ČR GA206/07/0378; GA ČR GD310/08/H077; GA AV ČR IAA600200704; GA MŠk 2B06155; GA MŠk LC07017
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: Earthworms * Invertebrates * Ferritin
    Kód oboru RIV: EC - Imunologie
    Impakt faktor: 2.341, rok: 2011

    Ferritin is a storage protein that plays a key role in iron metabolism. In this study, we report on the sequence characterization of a ferritin-coding cDNA in Eisenia andrei earthworms isolated by RT-PCR using degenerated primers, and we suggest the presence of a putative IRE in the 5′-UTR of ferritin mRNA. The obtained ferritin sequence was compared with those of other animals showing sequence and structure homology in consensus sites, including the iron-responsive element (IRE) and ferroxidase centers. Despite the sequence homology in the E. andrei mRNA of ferritin with the sequences of other animals in consensus IRE sites, the presented cytosine in the IRE of E. andrei ferritin in the expected position does not form a conventional bulge
    Trvalý link: http://hdl.handle.net/11104/0201662